Coronavirus: Research, Commentary, and News

The Science journals are striving to provide the best and most timely research, analysis, and news coverage of COVID-19 and the coronavirus that causes it. All content is free to access.

Read the latest: Science | Science Advances | Science Immunology | Science Robotics | Science Signaling | Science Translational Medicine | News from Science | Letters to the Editor | Book Reviews | Blogs


Networks of SARS-CoV-2 transmission
Muge Cevik and Stefan D. Baral
Perspective | Science Date: 9-Jul-2021 DOI: 10.1126/science.abg0842

Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants
Lingshu Wang et al.
Research Article | Science Date: 1-Jul-2021 DOI: 10.1126/science.abh1766

SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern
Matthew McCallum et al.
Research Article | Science Date: 1-Jul-2021 DOI: 10.1126/science.abi7994

Hybrid immunity
Shane Crotty
Perspective | Science Date: 25-Jun-2021 DOI: 10.1126/science.abj2258

Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity
Sophie M.-C. Gobeil et al.
Research Article | Science Date: 24-Jun-2021 DOI: 10.1126/science.abi6226

Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants
Yongfei Cai et al.
Research Article | Science Date: 24-Jun-2021 DOI: 10.1126/science.abi9745

Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2
Tia A. Tummino et al.
Research Article | Science Date: 22-Jun-2021 DOI: 10.1126/science.abi4708

Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice
David R. Martinez et al.
Research Article | Science Date: 22-Jun-2021 DOI: 10.1126/science.abi4506

Senolytics reduce coronavirus-related mortality in old mice
Christina D. Camell et al.
Research Article | Science Date: 8-Jun-2021 DOI: 10.1126/science.abe4832

Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets
Nunziata Maio et al.
Report | Science Date: 3-Jun-2021 DOI: 10.1126/science.abi5224

Estimating epidemiologic dynamics from cross-sectional viral load distributions
James A. Hay et al.
Research Article | Science Date: 3-Jun-2021 DOI: 10.1126/science.abh0635

Estimating infectiousness throughout SARS-CoV-2 infection course
Terry C. Jones et al.
Research Article | Science Date: 25-May-2021 DOI: 10.1126/science.abi5273

Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants
Meng Yuan et al.
Report | Science Date: 20-May-2021 DOI: 10.1126/science.abh1139

Face masks effectively limit the probability of SARS-CoV-2 transmission
Yafang Cheng et al.
Report | Science Date: 20-May-2021 DOI: 10.1126/science.abg6296

Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2
Jun Siong Low et al.
Report | Science Date: 18-May-2021 DOI: 10.1126/science.abg8985

Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome
Pramod R. Bhatt et al.
Research Article | Science Date: 13-May-2021 DOI: 10.1126/science.abf3546

Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes
William N. Voss et al.
Report | Science Date: 4-May-2021 DOI: 10.1126/science.abg5268

Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose
Catherine J. Reynolds et al.
Report | Science Date: 30-Apr-2021 DOI: 10.1126/science.abh1282

How SARS-CoV-2 first adapted in humans
Hyeryun Choe and Michael Farzan
Perspective | Science Date: 30-Apr-2021 DOI: 10.1126/science.abi4711

Household COVID-19 risk and in-person schooling
Justin Lessler et al.
Report | Science Date: 29-Apr-2021 DOI: 10.1126/science.abh2939

Socioeconomic status determines COVID-19 incidence and related mortality in Santiago, Chile
Gonzalo E. Mena, Pamela P. Martinez, Ayesha S. Mahmud, Pablo A. Marquet, Caroline O. Buckee, Mauricio Santillana
Research Article | Science Date: 27-Apr-2021 DOI: 10.1126/science.abg5298

Noncanonical crRNAs derived from host transcripts enable multiplexable RNA detection by Cas9
Chunlei Jiao et al.
Research Article | Science Date: 27-Apr-2021 DOI: 10.1126/science.abe7106

Resurgence of SARS-CoV-2: detection by community viral surveillance
Steven Riley et al.
Report | Science Date: 23-Apr-2021 DOI: 10.1126/science.abf0874

Addressing racial inequities in medicine
Malika A. Fair and Sherese B. Johnson
Perspective | Science Date: 23-Apr-2021 DOI: 10.1126/science.abf6738

Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil
Nuno R. Faria et al.
Research Article | Science Date: 14-Apr-2021 DOI: 10.1126/science.abh2644

Shared B cell memory to coronaviruses and other pathogens varies in human age groups and tissues
Fan Yang et al.
Report | Science Date: 12-Apr-2021 DOI: 10.1126/science.abf6648

X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease
Sebastian Günther et al.
Report | Science Date: 2-Apr-2021 DOI: 10.1126/science.abf7945

The emerging plasticity of SARS-CoV-2
Kevin D. McCormick, Jana L. Jacobs, John W. Mellors
Perspective | Science Date: 26-Mar-2021 DOI: 10.1126/science.abg4493

mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection
Leonidas Stamatatos et al.
Report | Science Date: 25-Mar-2021 DOI: 10.1126/science.abg9175

The impact of population-wide rapid antigen testing on SARS-CoV-2 prevalence in Slovakia
Martin Pavelka et al.
Report | Science Date: 23-Mar-2021 DOI: 10.1126/science.abf9648

SARS-CoV-2 transmission without symptoms
Angela L. Rasmussen and Saskia V. Popescu
Perspective | Science Date: 19-Mar-2021 DOI: 10.1126/science.abf9569

Timing the SARS-CoV-2 index case in Hubei province
Jonathan Pekar, Michael Worobey, Niema Moshiri, Konrad Scheffler, Joel O. Wertheim
Report | Science Date: 18-Mar-2021 DOI: 10.1126/science.abf8003

Structural impact on SARS-CoV-2 spike protein by D614G substitution
Jun Zhang et al.
Report | Science Date: 16-Mar-2021 DOI: 10.1126/science.abf2303

SARS-CoV-2 within-host diversity and transmission
Katrina A. Lythgoe et al.
Research Article | Science Date: 9-Mar-2021 DOI: 10.1126/science.abg0821

Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes
Chadi M. Saad-Roy et al.
Research Article | Science Date: 9-Mar-2021 DOI: 10.1126/science.abg8663

Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England
Nicholas G. Davies et al.
Research Article | Science Date: 3-Mar-2021 DOI: 10.1126/science.abg3055

SARS-CoV-2 dependence on host pathways
Jason P. Wong and Blossom Damania
Perspective | Science Date: 26-Feb-2021 DOI: 10.1126/science.abg6837

Market design to accelerate COVID-19 vaccine supply
Juan Camilo Castillo et al.
Policy Forum | Science Date: 25-Feb-2021 DOI: 10.1126/science.abg0889

SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model
Jingxin Qiao et al.
Report | Science Date: 18-Feb-2021 DOI: 10.1126/science.abf1611

Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets
Rory D. de Vries et al.
Report | Science Date: 17-Feb-2021 DOI: 10.1126/science.abf4896

Tracking the UK SARS-CoV-2 outbreak
Martha I. Nelson
Perspective | Science Date: 12-Feb-2021 DOI: 10.1126/science.abg2297

Single-domain antibodies make a difference
Xavier Saelens and Bert Schepens
Perspective | Science Date: 12-Feb-2021 DOI: 10.1126/science.abg2294

Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape
Kevin R. McCarthy et al.
Report | Science Date: 3-Feb-2021 DOI: 10.1126/science.abf6950

Age groups that sustain resurging COVID-19 epidemics in the United States
Mélodie Monod et al.
Research Article | Science Date: 2-Feb-2021 DOI: 10.1126/science.abe8372

Neutralization of SARS-CoV-2 lineage B.1.1.7 pseudovirus by BNT162b2 vaccine–elicited human sera
Alexander Muik et al.
Report | Science Date: 29-Jan-2021 DOI: 10.1126/science.abg6105

China can help solve the debt and environmental crises
B. Alexander Simmons, Rebecca Ray, Hongbo Yang, Kevin P. Gallagher
Policy Forum | Science Date: 29-Jan-2021 DOI: 10.1126/science.abf4049

Lessons in antiviral immunity
Jennifer L. Hope and Linda M. Bradley
Perspective | Science Date: 29-Jan-2021 DOI: 10.1126/science.abf6446

Insights from SARS-CoV-2 sequences
Michael A. Martin, David Vanlnsberghe, Katia Koelle
Perspective | Science Date: 29-Jan-2021 DOI: 10.1126/science.abf3995

Prospective mapping of viral mutations that escape antibodies used to treat COVID-19
Tyler N. Starr et al.
Report | Science Date: 25-Jan-2021 DOI: 10.1126/science.abf9302

Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody
C. Garrett Rappazzo et al.
Research Article | Science Date: 25-Jan-2021 DOI: 10.1126/science.abf4830

Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A
Kris M. White et al.
Research Article | Science Date: 25-Jan-2021 DOI: 10.1126/science.abf4058

Optimizing age-specific vaccination
Meagan C. Fitzpatrick and Alison P. Galvani
Perspective | Science Date: 21-Jan-2021 DOI: 10.1126/science.abg2334

Model-informed COVID-19 vaccine prioritization strategies by age and serostatus
Kate M. Bubar et al.
Research Article | Science Date: 21-Jan-2021 DOI: 10.1126/science.abe6959

Herd immunity by infection is not an option
Devi Sridhar and Deepti Gurdasani
Perspective | Science Date: 15-Jan-2021 DOI: 10.1126/science.abf7921

Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
Paul-Albert Koenig et al.
Research Article | Science Date: 12-Jan-2021 DOI: 10.1126/science.abe6230

Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice
Alexander A. Cohen et al.
Report | Science Date: 12-Jan-2021 DOI: 10.1126/science.abf6840

Immunological characteristics govern the transition of COVID-19 to endemicity
Jennie S. Lavine, Ottar N. Bjornstad, Rustom Antia
Report | Science Date: 12-Jan-2021 DOI: 10.1126/science.abe6522

Establishment and lineage dynamics of the SARS-CoV-2 epidemic in the UK
Louis du Plessis et al.
Research Article | Science Date: 8-Jan-2021 DOI: 10.1126/science.abf2946

SARS-CoV-2 spillover events
Peng Zhou and Zheng-Li Shi
Perspective | Science Date: 8-Jan-2021 DOI: 10.1126/science.abf6097

Coevolution of policy and science during the pandemic
Yian Yin, Jian Gao, Benjamin F. Jones, Dashun Wang
Policy Forum | Science Date: 8-Jan-2021 DOI: 10.1126/science.abe3084

Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection
Jennifer M. Dan et al.
Research Article | Science Date: 6-Jan-2021 DOI: 10.1126/science.abf4063

COVID-19 and cancer in Africa
Beatrice Wiafe Addai and Wilfred Ngwa
Perspective | Science Date: 1-Jan-2021 DOI: 10.1126/science.abd1016

The puzzle of the COVID-19 pandemic in Africa
Justin M. Maeda and John N. Nkengasong
Perspective | Science Date: 1-Jan-2021 DOI: 10.1126/science.abf8832

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity
Mads Delbo Larsen et al.
Research Article | Science Date: 23-Dec-2020 DOI: 10.1126/science.abc8378

COVID-19 testing: One size does not fit all
Michael J. Mina and Kristian G. Andersen
Perspective | Science Date: 21-Dec-2020 DOI: 10.1126/science.abe9187

Inferring the effectiveness of government interventions against COVID-19
Jan M. Brauner et al.
Research Article | Science Date: 15-Dec-2020 DOI: 10.1126/science.abd9338

Remembering seasonal coronaviruses
Jenna J. Guthmiller and Patrick C. Wilson
Perspective | Science Date: 11-Dec-2020 DOI: 10.1126/science.abf4860

Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events
Jacob E. Lemieux et al.
Research Article | Science Date: 10-Dec-2020 DOI: 10.1126/science.abe3261

Three-quarters attack rate of SARS-CoV-2 in the Brazilian Amazon during a largely unmitigated epidemic
Lewis F. Buss et al.
Report | Science Date: 8-Dec-2020 DOI: 10.1126/science.abe9728

COVID-19 vaccine trial ethics once we have efficacious vaccines
David Wendler, Jorge Ochoa, Joseph Millum, Christine Grady, Holly A. Taylor
Policy Forum | Science Date: 3-Dec-2020 DOI: 10.1126/science.abf5084

Transmission heterogeneities, kinetics, and controllability of SARS-CoV-2
Kaiyuan Sun et al.
Research Article | Science Date: 24-Nov-2020 DOI: 10.1126/science.abe2424

Ensuring vaccine safety
David M. Knipe, Ofer Levy, Katherine A. Fitzgerald, Elke Mühlberger
Perspective | Science Date: 17-Nov-2020 DOI: 10.1126/science.abf0357

What’s next for COVID-19 apps? Governance and oversight
Alessandro Blasimme and Effy Vayena
Policy Forum | Science Date: 13-Nov-2020 DOI: 10.1126/science.abd9006

SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo
Yixuan J. Hou et al.
Report | Science Date: 12-Nov-2020 DOI: 10.1126/science.abe8499

Seroprevalence of anti–SARS-CoV-2 IgG antibodies in Kenyan blood donors
Sophie Uyoga et al.
Report | Science Date: 11-Nov-2020 DOI: 10.1126/science.abe1916

Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans
Bas B. Oude Munnink et al.
Report | Science Date: 10-Nov-2020 DOI: 10.1126/science.abe5901

Preexisting and de novo humoral immunity to SARS-CoV-2 in humans
Kevin W. Ng et al.
Report | Science Date: 6-Nov-2020 DOI: 10.1126/science.abe1107

Public health during the pandemic in India
Jacob John and Gagandeep Kang
Perspective | Science Date: 6-Nov-2020 DOI: 10.1126/science.abe9707

Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2
Yufei Xiang et al.
Report | Science Date: 5-Nov-2020 DOI: 10.1126/science.abe4747

De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2
Thomas W. Linsky et al.
Report | Science Date: 5-Nov-2020 DOI: 10.1126/science.abe0075

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike
Michael Schoof et al.
Report | Science Date: 5-Nov-2020 DOI: 10.1126/science.abe3255

Robust neutralizing antibodies to SARS-CoV-2 infection persist for months
Ania Wajnberg et al.
Report | Science Date: 28-Oct-2020 DOI: 10.1126/science.abd7728

The engines of SARS-CoV-2 spread
Elizabeth C. Lee, Nikolas I. Wada, M. Kate Grabowski, Emily S. Gurley, Justin Lessler
Perspective | Science Date: 23-Oct-2020 DOI: 10.1126/science.abd8755

Susceptibility to severe COVID-19
David B. Beck and Ivona Aksentijevich
Perspective | Science Date: 23-Oct-2020 DOI: 10.1126/science.abe7591

Understanding COVID-19 vaccine efficacy
Marc Lipsitch and Natalie E. Dean
Perspective | Science Date: 21-Oct-2020 DOI: 10.1126/science.abe5938

Neuropilin-1 is a host factor for SARS-CoV-2 infection
James L. Daly et al.
Report | Science Date: 20-Oct-2020 DOI: 10.1126/science.abd3072

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate
Sandhya Bangaru et al.
Report | Science Date: 20-Oct-2020 DOI: 10.1126/science.abe1502

Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity
Ludovico Cantuti-Castelvetri et al.
Report | Science Date: 20-Oct-2020 DOI: 10.1126/science.abd2985

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
David E. Gordon et al.
Research Article | Science Date: 15-Oct-2020 DOI: 10.1126/science.abe9403

REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters
Alina Baum et al.
Report | Science Date: 9-Oct-2020 DOI: 10.1126/science.abe2402

Inhibiting Ebola virus and SARS-CoV-2 entry
Alexandra I. Wells and Carolyn B. Coyne
Perspective | Science Date: 9-Oct-2020 DOI: 10.1126/science.abe2977

Epidemiology and transmission dynamics of COVID-19 in two Indian states
Ramanan Laxminarayan et al.
Research Article | Science Date: 30-Sep-2020 DOI: 10.1126/science.abd7672

Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity
Ellen Shrock et al.
Report | Science Date: 29-Sep-2020 DOI: 10.1126/science.abd4250

Auto-antibodies against type I IFNs in patients with life-threatening COVID-19
Paul Bastard et al.
Research Article | Science Date: 24-Sep-2020 DOI: 10.1126/science.abd4585

Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms
M. Alejandra Tortorici et al.
Research Article | Science Date: 24-Sep-2020 DOI: 10.1126/science.abe3354

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
Qian Zhang et al.
Research Article | Science Date: 24-Sep-2020 DOI: 10.1126/science.abd4570

COVID-19 can affect the heart
Eric J. Topol
Perspective | Science Date: 23-Sep-2020 DOI: 10.1126/science.abe2813

Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein
Christine Toelzer et al.
Report | Science Date: 21-Sep-2020 DOI: 10.1126/science.abd3255

Immune life history, vaccination, and the dynamics of SARS-CoV-2 over the next 5 years
Chadi M. Saad-Roy et al.
Research Article | Science Date: 21-Sep-2020 DOI: 10.1126/science.abd7343

COVID-19 in children and young people
Matthew D. Snape and Russell M. Viner
Perspective | Science Date: 21-Sep-2020 DOI: 10.1126/science.abd6165

Will SARS-CoV-2 become endemic?
Jeffrey Shaman and Marta Galanti
Perspective | Science Date: 14-Oct-2020 DOI: 10.1126/science.abe5960

Trump lied about science
H. Holden Thorp
Editorial | Science Date: 11-Sep-2020 DOI: 10.1126/science.abe7391

Coronavirus dons a new crown
Nuruddin Unchwaniwala and Paul Ahlquist
Perspective | Science Date: 11-Sep-2020 DOI: 10.1126/science.abe0322

The emergence of SARS-CoV-2 in Europe and North America
Michael Worobey et al.
Research Article | Science Date: 10-Sep-2020 DOI: 10.1126/science.abc8169

Cryptic transmission of SARS-CoV-2 in Washington state
Trevor Bedford et al.
Report | Science Date: 10-Sep-2020 DOI: 10.1126/science.abc0523

De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
Longxing Cao et al.
Research Article | Science Date: 9-Sep-2020 DOI: 10.1126/science.abd9909

Reopening schools during COVID-19
Ronan Lordan, Garret A. FitzGerald, Tilo Grosser
Editorial | Science Date: 4-Sep-2020 DOI: 10.1126/science.abe5765

A molecular trap against COVID-19
Brandon J. DeKosky
Perspective | Science Date: 4-Sep-2020 DOI: 10.1126/science.abe0010

An ethical framework for global vaccine allocation
Ezekiel J. Emanuel
Policy Forum | Science Date: 3-Sep-2020 DOI: 10.1126/science.abe2803

Bridging digital health divides
Anurag Agrawal
Perspective | Science Date: 28-Aug-2020 DOI: 10.1126/science.abc9295

MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses
Anna Bruchez et al.
Report | Science Date: 27-Aug-2020 DOI: 10.1126/science.abb3753

In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges
Beata Turoňová et al.
Research Article | Science Date: 18-Aug-2020 DOI: 10.1126/science.abd5223

Vaccine nationalism’s politics
David P. Fidler
Editorial | Science Date: 14-Aug-2020 DOI: 10.1126/science.abe2275

A dangerous rush for vaccines
H. Holden Thorp
Editorial | Science Date: 13-Aug-2020 DOI: 10.1126/science.abe3147

Knowledge transfer for large-scale vaccine manufacturing
W. Nicholson Price II, Arti K. Rai, Timo Minssen
Policy Forum | Science Date: 13-Aug-2020 DOI: 10.1126/science.abc9588

Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans
Prabhu S. Arunachalam et al.
Research Article | Science Date: 11-Aug-2020 DOI: 10.1126/science.abc6261

COVID-19 in Africa: Dampening the storm?
Moustapha Mbow et al.
Perspective | Science Date: 7-Aug-2020 DOI: 10.1126/science.abd3902

Productivity in a pandemic
Caitlyn Collins
Editorial | Science Date: 7-Aug-2020 DOI: 10.1126/science.abe1163

Interferon responses in viral pneumonias
Gary E. Grajales-Reyes and Marco Colonna
Perspective | Science Date: 7-Aug-2020 DOI: 10.1126/science.abd2208

A molecular pore spans the double membrane of the coronavirus replication organelle
Georg Wolff et al.
Report | Science Date: 6-Aug-2020 DOI: 10.1126/science.abd3629

Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2
Kui K. Chan et al.
Report | Science Date: 4-Aug-2020 DOI: 10.1126/science.abc0870

Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans
Jose Mateus et al.
Research Article | Science Date: 4-Aug-2020 DOI: 10.1126/science.abd3871

Cautious optimism
H. Holden Thorp
Editorial | Science Date: 31-Jul-2020 DOI: 10.1126/science.abe0359

How does SARS-CoV-2 cause COVID-19?
Nicholas J. Matheson and Paul J. Lehner
Perspective | Science Date: 31-Jul-2020 DOI: 10.1126/science.abc6156

COVID-19 risks to global food security
David Laborde, Will Martin, Johan Swinnen, Rob Vos
Policy Forum | Science Date: 31-Jul-2020 DOI: 10.1126/science.abc4765

Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy
Hongjing Gu et al.
Research Article | Science Date: 30-Jul-2020 DOI: 10.1126/science.abc4730

COVID-19 affects HIV and tuberculosis care
Quarraisha Abdool Karim and Salim S. Abdool Karim
Perspective | Science Date: 24-Jul-2020 DOI: 10.1126/science.abd1072

Mathematical models to guide pandemic response
C. Jessica E. Metcalf, Dylan H. Morris, Sang Woo Park
Perspective | Science Date: 24-Jul-2020 DOI: 10.1126/science.abd1668

The COVID-19 pandemic and human fertility
A. Aassve, N. Cavalli, L. Mencarini, S. Plach, M. Livi Bacci
Perspective | Science Date: 24-Jul-2020 DOI: 10.1126/science.abc9520

Ecology and economics for pandemic prevention
Andrew P. Dobson et al.
Policy Forum | Science Date: 24-Jul-2020 DOI: 10.1126/science.abc3189

Structure-based design of prefusion-stabilized SARS-CoV-2 spikes
Ching-Lin Hsieh et al.
Report | Science Date: 23-Jul-2020 DOI: 10.1126/science.abd0826

Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody
Zhe Lv et al.
Report | Science Date: 23-Jul-2020 DOI: 10.1126/science.abc5881

Evolution and epidemic spread of SARS-CoV-2 in Brazil
Darlan S. Candido et al.
Report | Science Date: 23-Jul-2020 DOI: 10.1126/science.abd2161

Distinct conformational states of SARS-CoV-2 spike protein
Yongfei Cai et al.
Research Article | Science Date: 21-Jul-2020 DOI: 10.1126/science.abd4251

Serial interval of SARS-CoV-2 was shortened over time by nonpharmaceutical interventions
Sheikh Taslim Ali et al.
Report | Science Date: 21-Jul-2020 DOI: 10.1126/science.abc9004

Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2
Matthias Thoms et al.
Report | Science Date: 17-Jul-2020 DOI: 10.1126/science.abc8665

Assessing the impact of coordinated COVID-19 exit strategies across Europe
N. W. Ruktanonchai et al.
Research Article | Science Date: 17-Jul-2020 DOI: 10.1126/science.abc5096

Aging immunity may exacerbate COVID-19
Arne N. Akbar, Derek W. Gilroy
Perspective | Science Date: 17-Jul-2020 DOI: 10.1126/science.abb0762

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications
Divij Mathew et al.
Research Article | Science Date: 15-Jul-2020 DOI: 10.1126/science.abc8511

Structural basis of a shared antibody response to SARS-CoV-2
Meng Yuan et al.
Report | Science Date: 13-Jul-2020 DOI: 10.1126/science.abd2321

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients
Jérôme Hadjadj et al.
Report | Science Date: 13-Jul-2020 DOI: 10.1126/science.abc6027

Rigorous wildlife disease surveillance
M. Watsa and Wildlife Disease Surveillance Focus Group
Perspective | Science Date: 10-Jul-2020 DOI: 10.1126/science.abc0017

Surviving the trauma of COVID-19
Roxane Cohen Silver
Editorial | Science Date: 3-Jul-2020 DOI: 10.1126/science.abd5396

Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques
Wei Deng et al.
Report | Science Date: 2-Jul-2020 DOI: 10.1126/science.abc5343

A mathematical model reveals the influence of population heterogeneity on herd immunity to SARS-CoV-2
Tom Britton et al.
Report | Science Date: 23-Jun-2020 DOI: 10.1126/science.abc6810

A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2
Xiangyang Chi et al.
Research Article | Science Date: 22-Jun-2020 DOI: 10.1126/science.abc6952

COVID-19 and cancer
Norman E. Sharpless
Editorial | Science Date: 19-Jun-2020 DOI: 10.1126/science.abd3377

Unexpected air pollution with marked emission reductions during the COVID-19 outbreak in China
Tianhao Le et al.
Report | Science Date: 17-Jun-2020 DOI: 10.1126/science.abb7431

Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies
Alina Baum et al.
Report | Science Date: 15-Jun-2020 DOI: 10.1126/science.abd0831

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability
Philip J. M. Brouwer et al.
Research Article | Science Date: 15-Jun-2020 DOI: 10.1126/science.abc5902

Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail
Johanna Hansen et al.
Report | Science Date: 15-Jun-2020 DOI: 10.1126/science.abd0827

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model
Thomas F. Rogers et al.
Research Article | Science Date: 15-Jun-2020 DOI: 10.1126/science.abc7520

Broad neutralization of SARS-related viruses by human monoclonal antibodies
A. Z. Wec et al.
Report | Science Date: 15-Jun-2020 DOI: 10.1126/science.abc7424

The impact of COVID-19 and strategies for mitigation and suppression in low- and middle-income countries
Patrick G. T. Walker
Research Article | Science Date: 12-Jun-2020 DOI: 10.1126/science.abc0035

COVID-19 and flu, a perfect storm
Edward A. Belongia, Michael T. Osterholm
Editorial | Science Date: 12-Jun-2020 DOI: 10.1126/science.abd2220

Type I and III interferons disrupt lung epithelial repair during recovery from viral infection
Jack Major et al.
Report | Science Date: 11-Jun-2020 DOI: 10.1126/science.abc2061

Type III interferons disrupt the lung epithelial barrier upon viral recognition
Achille Broggi et al.
Report | Science Date: 11-Jun-2020 DOI: 10.1126/science.abc3545

Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California
Xianding Deng et al.
Report | Science Date: 8-Jun-2020 DOI: 10.1126/science.abb9263

Patents, economics, and pandemics
Will Zerhouni, Gary J. Nabel, Elias Zerhouni
Editorial | Science Date: 5-Jun-2020 DOI: 10.1126/science.abc7472

Introductions and early spread of SARS-CoV-2 in the New York City area
A. S. Gonzalez-Reiche et al.
Report | Science Date: 29-May-2020 DOI: 10.1126/science.abc1917

COVID-19 research in Africa
Linda-Gail Bekker, Valerie Mizrahi
Editorial | Science Date: 29-May-2020 DOI: 10.1126/science.abc9528

Moving academic research forward during COVID-19
N. S. Wigginton et al.
Policy Forum | Science Date: 28-May-2020 DOI: 10.1126/science.abc5599

Reducing transmission of SARS-CoV-2
Kimberly A. Prather, Chia C. Wang, Robert T. Schooley
Perspective | Science Date: 27-May-2020 DOI: 10.1126/science.abc6197

Suspend tests and rankings
H. Holden Thorp
Editorial | Science Date: 22-May-2020 DOI: 10.1126/science.abc8654

Which interventions work best in a pandemic?
J. Haushofer, C. J. E. Metcalf
Policy Forum | Science Date: 21-May-2020 DOI: 10.1126/science.abb6144

DNA vaccine protection against SARS-CoV-2 in rhesus macaques
Jingyou Yu et al.
Research Article | Science Date: 20-May-2020 DOI: 10.1126/science.abc6284

SARS-CoV-2 infection protects against rechallenge in rhesus macaques
Abishek Chandrashekar et al.
Research Article | Science Date: 20-May-2020 DOI: 10.1126/science.abc4776

Susceptible supply limits the role of climate in the early SARS-CoV-2 pandemic
Rachel E. Baker, Wenchang Yang, Gabriel A. Vecchi, C. Jessica E. Metcalf, Bryan T. Grenfell
Report | Science Date: 18-May-2020 DOI: 10.1126/science.abc2535

Serology assays to manage COVID-19
Florian Krammer, Viviana Simon
Perspective | Science Date: 15-May-2020 DOI: 10.1126/science.abc1227

Inferring change points in the spread of COVID-19 reveals the effectiveness of interventions
Jonas Dehning et al.
Research Article | Science Date: 15-May-2020 DOI: 10.1126/science.abb9789

Policy opportunity to enhance sharing for pandemic research
Michelle Rourke et al.
Policy Forum | Science Date: 15-May-2020 DOI: 10.1126/science.abb9342

Lessons from the crucible of crisis
Marcia McNutt
Editorial | Science Date: 15-May-2020 DOI: 10.1126/science.abc6866

Estimating the burden of SARS-CoV-2 in France
Henrik Salje et al.
Report | Science Date: 13-May-2020 DOI: 10.1126/science.abc3517

A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2
Yan Wu et al.
Report | Science Date: 13-May-2020 DOI: 10.1126/science.abc2241

Ethics and governance for digital disease surveillance
M. M. Mello and C. J. Wang
Policy Forum | Science Date: 11-May-2020 DOI: 10.1126/science.abb9045

A strategic approach to COVID-19 vaccine R&D
Lawrence Corey, John R. Mascola, Anthony S. Fauci, Francis S. Collins
Policy Forum | Science Date: 11-May-2020 DOI: 10.1126/science.abc5312

Both/and problem in an either/or world
H. Holden Thorp
Editorial | Science Date: 8-May-2020 DOI: 10.1126/science.abc6859

Rapid COVID-19 vaccine development
Barney S. Graham
Perspective | Science Date: 8-May-2020 DOI: 10.1126/science.abb8923

Rapid repurposing of drugs for COVID-19
R. K. Guy et al.
Perspective | Science Date: 8-May-2020 DOI: 10.1126/science.abb9332

Combination prevention for COVID-19
Myron S. Cohen and Lawrence Corey
Editorial | Science Date: 8-May-2020 DOI: 10.1126/science.abc5798

Beat COVID-19 through innovation
Pierre Azoulay and Benjamin Jones
Editorial | Science Date: 8-May-2020 DOI: 10.1126/science.abc5792

Ethics of controlled human infection to study COVID-19
S. K. Shah et al.
Policy Forum | Science Date: 7-May-2020 DOI: 10.1126/science.abc1076

Rapid development of an inactivated vaccine candidate for SARS-CoV-2
Qiang Gao et al.
Report | Science Date: 6-May-2020 DOI: 10.1126/science.abc1932

Rapid implementation of mobile technology for real-time epidemiology of COVID-19
David A. Drew et al.
Report | Science Date: 5-May-2020 DOI: 10.1126/science.abc0473

Site-specific glycan analysis of the SARS-CoV-2 spike
Yasunori Watanabe et al.
Report | Science Date: 4-May-2020 DOI: 10.1126/science.abb9983

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir
Wanchao Yin et al.
Report | Science Date: 1-May-2020 DOI: 10.1126/science.abc1560

SARS-CoV-2 productively infects human gut enterocytes
Mart M. Lamers et al.
Research Article | Science Date: 1-May-2020 DOI: 10.1126/science.abc1669

COVID-19 amidst Ebola's retreat
John Ditekemena
Editorial | Science Date: 1-May-2020 DOI: 10.1126/science.abc4859

A COVID-19 recovery for climate
Daniel Rosenbloom and Jochen Markard
Editorial | Science Date: 1-May-2020 DOI: 10.1126/science.abc4887

Changes in contact patterns shape the dynamics of the COVID-19 outbreak in China
Juanjuan Zhang et al.
Report | Science Date: 29-Apr-2020 DOI: 10.1126/science.abb8001

Modeling infectious disease dynamics
Sarah Cobey
Perspective | Science Date: 24-Apr-2020 DOI: 10.1126/science.abb5659

Lost in transition
Kathleen Newland
Editorial | Science Date: 24-Apr-2020 DOI: 10.1126/science.abc3197

Against pandemic research exceptionalism
Alex John London, Jonathan Kimmelman
Policy Forum | Science Date: 23-Apr-2020 DOI: 10.1126/science.abc1731

Structure-b​ased design of antiviral drug candidates targeting the SARS-CoV-2 main protease
W. Dai et al.
Research Article | Science Date: 22-Apr-2020 DOI: 10.1126/science.abb4489

Why WHO?
H. Holden Thorp
Editorial | Science Date: 20-Apr-2020 DOI: 10.1126/science.abc3400

Comparative pathogenesis of COVID-19, MERS and SARS in a non-human primate model
Barry Rockx et al.
Report | Science Date: 17-Apr-2020 DOI: 10.1126/science.abb7314

Cytokine release syndrome in severe COVID-19
John B. Moore, Carl H. June
Perspective | Science Date: 17-Apr-2020 DOI: 10.1126/science.abb8925

The moment to see the poor
Joachim von Braun, Stefano Zamagni, Marcelo Sánchez Sorondo
Editorial | Science Date: 17-Apr-2020 DOI: 10.1126/science.abc2255

Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period
Stephen M. Kissler, Christine Tedijanto, Edward Goldstein, Yonatan H. Grad, Marc Lipsitch
Report | Science Date: 14-Apr-2020 DOI: 10.1126/science.abb5793

Structure of the RNA-dependent RNA polymerase from COVID-19 virus
Yan Gao et al.
Report | Science Date: 10-Apr-2020 DOI: 10.1126/science.abb7498

G20 leaders must answer to COVID-19
Caroline Atkinson
Editorial | Science Date: 10-Apr-2020 DOI: 10.1126/science.abc1025

Effective containment explains sub-exponential growth in recent confirmed COVID-19 cases in China 
Benjamin F. Maier, Dirk Brockmann
Research Article | Science Date: 8-Apr-2020 DOI: 10.1126/science.abb4557

Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus-2 
Jianzhong Shi et al.
Report | Science Date: 8-Apr-2020 DOI: 10.1126/science.abb7015

A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV
Meng Yuan, Nicholas C. Wu, Xueyong Zhu, Chang-Chun D. Lee, Ray T. Y. So, Huibin Lv, Chris K. P. Mok, Ian A. Wilson
Report | Science Date: 3-Apr-2020 DOI: 10.1126/science.abb7269

Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing
Luca Ferretti, Chris Wymant, Michelle Kendall, Lele Zhao, Anel Nurtay, Lucie Abeler-Dörner, Michael Parker, David Bonsall, Christophe Fraser
Research Article | Science Date: 31-Mar-2020 DOI: 10.1126/science.abb6936

An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China
Huaiyu Tian, Yonghong Liu, Yidan Li, Chieh-Hsi Wu, Bin Chen, Moritz U. G. Kraemer, Bingying Li, Jun Cai, Bo Xu, Qiqi Yang, Ben Wang, Peng Yang, Yujun Cui, Yimeng Song, Pai Zheng, Quanyi Wang, Ottar N. Bjornstad, Ruifu Yang, Bryan T. Grenfell, Oliver G. Pybus, Christopher Dye
Report | Science Date: 31-Mar-2020 DOI: 10.1126/science.abb6105

This is real
H. Holden Thorp
Editorial | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb9223

COVID-19 needs a big science approach
Seth Berkley
Editorial | Science Date: 25-Mar-2020 DOI: 10.1126/science.abb8654

The effect of human mobility and control measures on the COVID-19 epidemic in China
Moritz U. G. Kraemer, Chia-Hung Yang, Bernardo Gutierrez, Chieh-Hsi Wu, Brennan Klein, David M. Pigott, Open COVID-19 Data Working Group, Louis du Plessis, Nuno R. Faria, Ruoran Li, William P. Hanage, John S. Brownstein, Maylis Layan, Alessandro Vespignani, Huaiyu Tian, Christopher Dye, Oliver G. Pybus, Samuel V. Scarpino
Research Article | Science Date: 25-Mar-2020 DOI: 10.1126/science.abb4218

Underpromise, overdeliver
H. Holden Thorp
Editorial | Science Date: 23-Mar-2020 DOI: 10.1126/science.abb8492

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
Linlin Zhang, Daizong Lin, Xinyuanyuan Sun, Ute Curth, Christian Drosten, Lucie Sauerhering, Stephan Becker, Katharina Rox, Rolf Hilgenfeld
Report | Science Date: 20-Mar-2020 DOI: 10.1126/science.abb3405

Time to pull together
H. Holden Thorp
Editorial | Science Date: 16-Mar-2020 DOI: 10.1126/science.abb7518

Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2)
Ruiyun Li, Sen Pei, Bin Chen, Yimeng Song, Tao Zhang, Wan Yang, Jeffrey Shaman
Research Article | Science Date: 16-Mar-2020 DOI: 10.1126/science.abb3221 

Do us a favor
H. Holden Thorp
Editorial | Science Date: 11-Mar-2020 DOI: 10.1126/science.abb6502

The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak
Matteo Chinazzi, Jessica T. Davis, Marco Ajelli, Corrado Gioannini, Maria Litvinova, Stefano Merler, Ana Pastore y Piontti, Kunpeng Mu, Luca Rossi, Kaiyuan Sun, Cécile Viboud, Xinyue Xiong, Hongjie Yu, M. Elizabeth Halloran, Ira M. Longini Jr., Alessandro Vespignani
Research Article | Science Date: 6-Mar-2020 DOI: 10.1126/science.aba9757

Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2
Renhong Yan, Yuanyuan Zhang, Yaning Li, Lu Xia, Yingying Guo, Qiang Zhou
Research Article | Science Date: 4-Mar-2020 DOI: 10.1126/science.abb2762

The costs of secrecy
H. Holden Thorp
Editorial | Science Date: 28-Feb-2020 DOI: 10.1126/science.abb4420

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Daniel Wrapp, Nianshuang Wang, Kizzmekia S. Corbett, Jory A. Goldsmith, Ching-Lin Hsieh, Olubukola Abiona, Barney S. Graham, Jason S. McLellan
Report | Science Date: 19-Feb-2020 DOI: 10.1126/science.abb2507

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Science Advances

Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11
J. Fedry et al.
Research Article | Science Advances Date: 6-May-2021 DOI: 10.1126/sciadv.abf5632

SARS-CoV-2 can recruit a haem metabolite to evade antibody immunity
A. Rosa et al.
Research Article | Science Advances Date: 22-Apr-2021 DOI: 10.1126/sciadv.abg7607

Anatomy of digital contact tracing: Role of age, transmission setting, adoption and case detection
J. A. Moreno López et al.
Research Article | Science Advances Date: 12-Mar-2021 DOI: 10.1126/sciadv.abd8750

Immunogenicity of clinically relevant SARS-CoV-2 vaccines in non-human primates and humans
P. J. Klasse et al.
Review | Science Advances Date: 19-Feb-2021 DOI: 10.1126/sciadv.abe8065

A smartphone-read ultrasensitive and quantitative saliva test for COVID-19
B. Ning et al.
Research Article | Science Advances Date: 11-Dec-2020 DOI: 10.1126/sciadv.abe3703

Partisan pandemic: How partisanship and public health concerns affect individuals’ social mobility during COVID-19
J. Clinton et al.
Research Article | Science Advances Date: 11-Dec-2020 DOI: 10.1126/sciadv.abd7204

Airflows inside passenger cars and implications for airborne disease transmission
V. Mathai et al.
Research Article | Science Advances Date: 4-Dec-2020 DOI: 10.1126/sciadv.abe0166

Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM
C. Xu et al.
Research Article | Science Advances Date: 4-Dec-2020 DOI: 10.1126/sciadv.abe5575

MBD2 serves as a viable target against pulmonary fibrosis by inhibiting macrophage M2 program
Y. Wang et al.
Research Article | Science Advances Date: 4-Dec-2020 DOI: 10.1126/sciadv.abb6075

Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening
D. B. Larremore et al.
Research Article | Science Advances Date: 20-Nov-2020 DOI: 10.1126/sciadv.abd5393

Damaged lung gas-exchange function of discharged COVID-19 patients detected by hyperpolarized 129Xe MRI
H. Li et al.
Research Article | Science Advances Date: 20-Nov-2020 DOI: 10.1126/sciadv.abc8180

JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality
J. Stebbing et al.
Research Article | Science Advances Date: 13-Nov-2020 DOI: 10.1126/sciadv.abe4724

Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm
P. A. Mudd et al.
Research Article | Science Advances Date: 13-Nov-2020 DOI: 10.1126/sciadv.abe3024

Differential effects of intervention timing on COVID-19 spread in the United States
S. Pei et al.
Research Article | Science Advances Date: 6-Nov-2020 DOI: 10.1126/sciadv.abd6370

Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against Mpro and cathepsin L
M. D. Sacco et al.
Research Article | Science Advances Date: 6-Nov-2020 DOI: 10.1126/sciadv.abe0751

Potency and timing of antiviral therapy as determinants of duration of SARS-CoV-2 shedding and intensity of inflammatory response
A. Goyal et al.
Research Article | Science Advances Date: 23-Oct-2020 DOI: 10.1126/sciadv.abc7112

Social connections with COVID-19–affected areas increase compliance with mobility restrictions
B. Charoenwong et al.
Research Article | Science Advances Date: 23-Oct-2020 DOI: 10.1126/sciadv.abc3054

Cross-reactive neutralization of SARS-CoV-2 by serum antibodies from recovered SARS patients and immunized animals
Y. Zhu et al.
Research Article | Science Advances Date: 9-Oct-2020 DOI: 10.1126/sciadv.abc9999

Model uncertainty, political contestation, and public trust in science: Evidence from the COVID-19 pandemic
S. E. Kreps and D. L. Kriner
Research Article | Science Advances Date: 25-Sep-2020 DOI: 10.1126/sciadv.abd4563

The unfolding COVID-19 pandemic: A probability-based, nationally representative study of mental health in the U.S.
E. A. Holman et al.
Research Article | Science Advances Date: 18-Sep-2020 DOI: 10.1126/sciadv.abd5390

Antibody-like proteins that capture and neutralize SARS-CoV-2
T. Kondo et al.
Research Article | Science Advances Date: 18-Sep-2020 DOI: 10.1126/sciadv.abd3916

Efficient high-throughput SARS-CoV-2 testing to detect asymptomatic carriers
N. Shental et al.
Research Article | Science Advances Date: 21-Aug-2020 DOI: 10.1126/sciadv.abc5961

Programmable low-cost DNA-based platform for viral RNA detection
L. Zhou et al.
Research Article | Science Advances Date: 21-Aug-2020 DOI: 10.1126/sciadv.abc6246

Molecular characterization of Ebselen binding activity to SARS-CoV-2 main protease
C. A. Menendez et al.
Research Article | Science Advances Date: 14-Aug-2020 DOI: 10.1126/sciadv.abd0345

Viruses harness YxxØ motif to interact with host AP2M1 for replication: a vulnerable broad-spectrum antiviral target
S. Yuan et al.
Research Article | Science Advances Date: 14-Aug-2020 DOI: 10.1126/sciadv.aba7910

Estimation of incubation period distribution of COVID-19 using disease onset forward time: a novel cross-sectional and forward follow-up study
J. Qin et al.
Research Article | Science Advances Date: 7-Aug-2020 DOI: 10.1126/sciadv.abc1202

Low-cost measurement of facemask efficacy for filtering expelled droplets during speech
Fischer et al.
Research Article | Science Advances Date: 7-Aug-2020 DOI: 10.1126/sciadv.abd3083

Mandated Bacillus Calmette-Guérin (BCG) vaccination predicts flattened curves for the spread of COVID-19
M. K. Berg et al.
Research Article | Science Advances Date: 31-Jul-2020 DOI: 10.1126/sciadv.abc1463

A single molecular descriptor to predict solution behavior of therapeutic antibodies
J. S. Kingsbury et al.
Research Article | Science Advances Date: 31-Jul-2020 DOI: 10.1126/sciadv.abb0372

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia
D. H. Brann et al.
Research Article | Science Advances  Date: 24-Jul-2020 DOI: 10.1126/sciadv.abc5801

Acetylated K676 TGFBIp as a severity diagnostic blood biomarker for SARS-CoV-2 pneumonia
H. H. Park et al.
Research Article | Science Advances  Date: 24-Jul-2020 DOI: 10.1126/sciadv.abc1564

Cancer did not stay home for COVID-19
R. L Levine
Editorial | Science Advances Date: 17-Jul-2020 DOI: 10.1126/sciadv.abd7487

Continuous on-body sensing for the COVID-19 pandemic: Gaps and opportunities
H. Jeong et al. 
Editorial | Science Advances Date: 1-Jul-2020 DOI: 10.1126/sciadv.abd4794 

Structure-based drug designing and immunoinformatics approach for SARS-CoV-2
Panda et al. 
Research Article | Science Advances Date: 24-Jun-2020 DOI: 10.1126/sciadv.abb8097

Elusive consensus: Polarization in elite communication on the COVID-19 pandemic
J.Green et al.
Research Article | Science Advances Date: 24-Jun-2020 DOI: 10.1126/sciadv.abc2717

Abrupt decline in tropospheric nitrogen dioxide over China after the outbreak of COVID-19
Fei Liu et al.
Research Article | Science Advances Date: 12-Jun-2020 DOI: 10.1126/sciadv.abc2992 

Pandemics and the global environment
Hodges and Jackson
Editorial | Science Advances Date: 12-Jun-2020 DOI: 10.1126/sciadv.abd1325 

Medical education in the time of COVID-19
D.B.Wayne et al.
Editorial | Science Advances Date: 5-Jun-2020 DOI: 10.1126/sciadv.abc7110 

COVID-19 and the next influenza season
Benjamin D. Singer
Editorial | Science Advances Date: 29-May-2020 DOI: 10.1126/sciadv.abd0086

Emergence of SARS-CoV-2 through Recombination and Strong Purifying Selection
Li et al.
Research Article | Science Advances Date: 29-May-2020 DOI: 10.1126/sciadv.abb9153

SARS-CoV-2 vaccines: Slow is fast
Douglas R. Green
Editorial | Science Advances Date: 22-May-2020 DOI: 10.1126/sciadv.abc7428

Evidence for host-dependent RNA editing in the transcriptome of SARS-CoV-2 in humans
Di Giorgio et al.
Research Article | Science Advances Date: 18-May-2020 DOI: 10.1126/sciadv.abb5813

COVID-19: Rescue by transcriptional inhibition
Ali Shilatifard
Editorial | Science Advances Date: 11-May-2020 DOI: 10.1126/sciadv.abc6891

Point of no return: COVID-19 and the US healthcare system
An emergency physician's perspective

Maia Dorsett
Editorial | Science Advances Date: 7-May-2020 DOI: 10.1126/sciadv.abc5354

A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques
Neeltje van Doremalen et al.
Research Article | Science Advances Date: 1-May-2020 DOI: 10.1126/sciadv.aba8399

Mobile phone data for informing public health actions across the COVID-19 pandemic lifecycle
Nuria Oliver, Bruno Lepri, Harald Sterly, Renaud Lambiotte, Sébastien Delataille, Marco De Nadai, Emmanuel Letouzé, Albert Ali Salah, Richard Benjamins, Ciro Cattuto, Vittoria Colizza, Nicolas de Cordes, Samuel P. Fraiberger, Til Koebe, Sune Lehmann, Juan Murillo, Alex Pentland, Phuong N. Pham, Frédéric Pivetta, Jari Saramaki, Samuel V. Scarpino, Michele Tizzoni, Stefaan Vehulst, Patrick Vinck
Editorial | Science Advances Date: 27-Apr-2020 DOI: 10.1126/sciadv.abc0764

Squalene-based multidrug nanoparticles for improved mitigation of uncontrolled inflammation
Flavio Dormont et al.
Research Article | Science Advances Date: 27-Apr-2020 DOI: 10.1126/sciadv.aaz5466

Medicine in the time of corona: Fundamental molecular research is “essential”
Ali Shilatifard
Editorial | Science Advances Date: 21-Apr-2020 DOI: 10.1126/sciadv.abc2800

Surviving COVID-19: A disease tolerance perspective
Janelle S. Ayres
Editorial | Science Advances Date: 17-Apr-2020 DOI: 10.1126/sciadv.abc1518

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Science Immunology

Implications of defective immune responses in SARS-CoV-2 vaccinated organ transplant recipients
Peter S. Heeger et al.
Editorial | Science Immunology Date: 1-Jul-2021 DOI: 10.1126/sciimmunol.abj6513

CD8+ T cells specific for conserved coronavirus epitopes correlate with milder disease in COVID-19 patients
Vamsee Mallajosyula et al.
Research Article | Science Immunology Date: 1-Jul-2021 DOI: 10.1126/sciimmunol.abg5669

Key epidemiological drivers and impact of interventions in the 2020 SARS-CoV-2 epidemic in England
Jonathan Sprent and Cecile King
Focus | Science Immunology Date: 22-Jun-2021 DOI: 10.1126/sciimmunol.abj9256

Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients
Hector Rincon-Arevalo et al.
Research Article | Science Immunology Date: 15-Jun-2021 DOI: 10.1126/sciimmunol.abj1031

SARS-CoV-2 vaccines elicit durable immune responses in infant rhesus macaques
Carolina Garrido et al.
Research Article | Science Immunology Date: 15-Jun-2021 DOI: 10.1126/sciimmunol.abj3684

Complement control for COVID-19
Markus Bosmann
Focus | Science Immunology Date: 25-May-2021 DOI: 10.1126/sciimmunol.abj1014

Polyclonal expansion of TCR Vbeta 21.3+ CD4+ and CD8+ T cells is a hallmark of Multisystem Inflammatory Syndrome in Children
Marion Moreews et al.
Research Article | Science Immunology Date: 25-May-2021 DOI: 10.1126/sciimmunol.abh1516

SARS-CoV-2 variants of concern partially escape humoral but not T-cell responses in COVID-19 convalescent donors and vaccinees
Daryl Geers et al.
Research Article | Science Immunology Date: 25-May-2021 DOI: 10.1126/sciimmunol.abj1750

A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection
Fiachra Humphries et al.
Research Article | Science Immunology Date: 18-May-2021 DOI: 10.1126/sciimmunol.abi9002

Pharmacological activation of STING blocks SARS-CoV-2 infection
Minghua Li et al.
Research Article | Science Immunology Date: 18-May-2021 DOI: 10.1126/sciimmunol.abi9007

Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection
Lina Ma et al.
Research Article | Science Immunology Date: 13-May-2021 DOI: 10.1126/sciimmunol.abh2259

Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals following mRNA vaccination
Rishi R. Goel et al.
Research Article | Science Immunology Date: 15-Apr-2021 DOI: 10.1126/sciimmunol.abi6950

SARS-CoV-2 genome-wide T cell epitope mapping reveals immunodominance and substantial CD8+ T cell activation in COVID-19 patients
Sunil Kumar Saini et al.
Research Article | Science Immunology Date: 14-Apr-2021 DOI: 10.1126/sciimmunol.abf7550

SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation
Bingyu Yan et al.
Research Article | Science Immunology Date: 7-Apr-2021 DOI: 10.1126/sciimmunol.abg0833

Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19
Ryan S. Thwaites et al.
Research Article | Science Immunology Date: 10-Mar-2021 DOI: 10.1126/sciimmunol.abg9873

SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8+ T cell responses
Benedikt Agerer et al.
Research Article | Science Immunology Date: 4-Mar-2021 DOI: 10.1126/sciimmunol.abg6461

Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19
Laura A. Vella et al.
Research Article | Science Immunology Date: 2-Mar-2021 DOI: 10.1126/sciimmunol.abf7570

Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients
Yu Zhao et al.
Research Article | Science Immunology Date: 23-Feb-2021 DOI: 10.1126/sciimmunol.abf6692

Prolonged evolution of the human B cell response to SARS-CoV-2 infection
Mrunal Sakharkar et al.
Research Article | Science Immunology Date: 23-Feb-2021 DOI: 10.1126/sciimmunol.abg6916

Severely ill COVID-19 patients display impaired exhaustion features in SARS-CoV-2-reactive CD8+ T cells
Anthony Kusnadi et al.
Research Article | Science Immunology Date: 21-Jan-2021 DOI: 10.1126/sciimmunol.abe4782

Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection
Catherine J. Reynolds et al.
Research Article | Science Immunology Date: 23-Dec-2020 DOI: 10.1126/sciimmunol.abf3698

Rapid generation of durable B cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 and convalescence
Gemma E. Hartley et al.
Report | Science Immunology Date: 22-Dec-2020 DOI: 10.1126/sciimmunol.abf8891

Defining the features and duration of antibody responses to SARS-CoV-2 infection associated with disease severity and outcome
Katharina Röltgen et al.
Research Article | Science Immunology Date: 7-Dec-2020 DOI: 10.1126/sciimmunol.abe0240

The known unknowns of T cell immunity to COVID-19
Annika C. Karlsson et al.
Perspective | Science Immunology Date: 18-Nov-2020 DOI: 10.1126/sciimmunol.abe8063

Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients
Baweleta Isho et al.
Research Article | Science Immunology Date: 8-Oct-2020 DOI: 10.1126/sciimmunol.abe5511

Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients
Anita S. Iyer et al.
Report | Science Immunology Date: 8-Oct-2020 DOI: 10.1126/sciimmunol.abe0367

MAIT cell activation and dynamics associated with COVID-19 disease severity
Tiphaine Parrot et al.
Report | Science Immunology Date: 28-Sep-2020 DOI: 10.1126/sciimmunol.abe1670

Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19
Elizabeth R. Mann et al.
Research Article | Science Immunology Date: 17-Sep-2020 DOI: 10.1126/sciimmunol.abd6197

Natural killer cell immunotypes related to COVID-19 disease severity
Christopher Maucourant et al.
Research Article | Science Immunology Date: 21-Aug-2020 DOI: 10.1126/sciimmunol.abd6832

SARS-CoV-2 seroprevalence among parturient women in Philadelphia
Dustin D. Flannery et al.
Report | Science Immunology Date: 29-Jul-2020 DOI: 10.1126/sciimmunol.abd5709

SARS-CoV-2 T cell immunity: Specificity, function, durability, and role in protection
Daniel M. Altmann and Rosemary J. Boyton
Perspective | Science Immunology Date: 17-Jul-2020 DOI: 10.1126/sciimmunol.abd6160

Comprehensive mapping of immune perturbations associated with severe COVID-19
Leticia Kuri-Cervantes et al.
Research Article | Science Immunology Date: 15-Jul-2020 DOI: 10.1126/sciimmunol.abd7114

Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19
Jeong Seok Lee et al.
Research Article | Science Immunology Date: 10-Jul-2020 DOI: 10.1126/sciimmunol.abd1554

Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome
Daniela Weiskopf et al.
Research Article | Science Immunology Date: 26-Jun-2020 DOI: 10.1126/sciimmunol.abd2071

The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients
Lakshmanane Premkumar et al.
Research Article | Science Immunology Date: 11-Jun-2020 DOI: 10.1126/sciimmunol.abc8413

Inhibition of Bruton tyrosine kinase in patients with severe COVID-19
Mark Roschewski et al.
Research Article | Science Immunology Date: 5-Jun-2020 DOI: 10.1126/sciimmunol.abd0110

Serology for SARS-CoV-2: Apprehensions, opportunities, and the path forward
Juliet E. Bryant et al.
Focus | Science Immunology Date: 19-May-2020 DOI: 10.1126/sciimmunol.abc6347

TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes
Ruochen Zang et al.
Research Article | Science Immunology Date: 13-May-2020 DOI: 10.1126/sciimmunol.abc3582

HiJAKing SARS-CoV-2? The potential role of JAK inhibitors in the management of COVID-19
Francesca Romana Spinelli et al.
Focus | Science Immunology Date: 8-May-2020 DOI: 10.1126/sciimmunol.abc5367

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Science Robotics

The potential of socially assistive robots during infectious disease outbreaks
Brian Scassellati and Marynel Vázquez
Research Article | Science Robotics Date: 15-Jul-2020 DOI: 10.1126/scirobotics.abc9014

Combating COVID-19—The role of robotics in managing public health and infectious diseases
Guang-Zhong Yang, Bradley J. Nelson, Robin R. Murphy, Howie Choset, Henrik Christensen, Steven H. Collins, Paolo Dario, Ken Goldberg, Koji Ikuta, Neil Jacobstein, Danica Kragic, Russell H. Taylor, Marcia McNutt
Editorial | Science Robotics Date: 25-Mar-2020 DOI: 10.1126/scirobotics.abb5589

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Science Signaling

Long-chain polyphosphates impair SARS-CoV-2 infection and replication
Veronica Ferrucci et al.
Research Article | Science Signaling Date: 06-Ju1-2021 DOI: 10.1126/scisignal.abe5040

Kynurenic acid may underlie sex-specific immune responses to COVID-19
Yuping Cai et al.
Research Article | Science Signaling Date: 06-Ju1-2021 DOI: 10.1126/scisignal.abf8483

Mn2+ coordinates Cap-0-RNA to align substrates for efficient 2′-O-methyl transfer by SARS-CoV-2 nsp16
George Minasov et al.
Research Article | Science Signaling Date: 15-Jun-2021 DOI: 10.1126/scisignal.abh2071

Short linear motif candidates in the cell entry system used by SARS-CoV-2 and their potential therapeutic implications
Bálint Mészáros et al.
Research Resource | Science Signaling Date: 12-Jan-2021 DOI: 10.1126/scisignal.abd0334

Cytoplasmic short linear motifs in ACE2 and integrin β3 link SARS-CoV-2 host cell receptors to mediators of endocytosis and autophagy
Johanna Kliche et al.
Research Article | Science Signaling Date: 12-Jan-2021 DOI: 10.1126/scisignal.abf1117

Kallikrein 13 serves as a priming protease during infection by the human coronavirus HKU1
Aleksandra Milewska et al.
Research Article | Science Signaling Date: 24-Nov-2020 DOI: 10.1126/scisignal.aba9902

High-resolution structures of the SARS-CoV-2 2′-O-methyltransferase reveal strategies for structure-based inhibitor design
Monica Rosas-Lemus et al.
Research Article | Science Signaling Date: 29-Sep-2020 DOI: 10.1126/scisignal.abe1202

COVID-19: All the wrong moves in all the wrong places
Christopher D. Barrett and Michael B. Yaffe
Editorial | Science Signaling Date: 15-Sep-2020 DOI: 10.1126/scisignal.abe4242

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Science Translational Medicine

Undiagnosed SARS-CoV-2 seropositivity during the first six months of the COVID-19 pandemic in the United States
Heather Kalish et al.
Report | Science Translational Medicine Date: 22-Jun-2021 DOI: 10.1126/scitranslmed.abh3826

Key epidemiological drivers and impact of interventions in the 2020 SARS-CoV-2 epidemic in England
Edward S. Knock et al.
Research Article | Science Translational Medicine Date: 22-Jun-2021 DOI: 10.1126/scitranslmed.abg4262

Serum neurofilament light protein correlates with unfavorable clinical outcomes in hospitalized patients with COVID-19
Mercedes Prudencio et al.
Report | Science Translational Medicine Date: 15-Jun-2021 DOI: 10.1126/scitranslmed.abi7643

Plasma from patients with bacterial sepsis or severe COVID-19 induces production of suppressive myeloid cells from human hematopoietic progenitor cells in vitro
Miguel Reyes et al.
Research Article | Science Translational Medicine Date: 8-Jun-2021 DOI: 10.1126/scitranslmed.abe9599

Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection
Allison J. Greaney et al.
Research Article | Science Translational Medicine Date: 8-Jun-2021 DOI: 10.1126/scitranslmed.abi9915

High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages
Willianne Hoepel et al.
Research Article | Science Translational Medicine Date: 11-May-2021 DOI: 10.1126/scitranslmed.abf8654

Viral genomes reveal patterns of the SARS-CoV-2 outbreak in Washington State
Nicola F. Müller et al.
Research Article | Science Translational Medicine Date: 3-May-2021 DOI: 10.1126/scitranslmed.abf0202

COVID-19-related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters
Guilherme Dias de Melo et al.
Research Article | Science Translational Medicine Date: 3-May-2021 DOI: 10.1126/scitranslmed.abf8396

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in non-human primates
Bryan E. Jones et al.
Research Article | Science Translational Medicine Date: 5-Ap-2021 DOI: 10.1126/scitranslmed.abf1906

T cell and antibody kinetics delineate SARS-CoV-2 peptides mediating long-term immune responses in COVID-19 convalescent individuals
Tatjana Bilich et al.
Research Article | Science Translational Medicine Date: 15-Mar-2021 DOI: 10.1126/scitranslmed.abf7517

SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19
Juan A. Perez-Bermejo et al.
Report | Science Translational Medicine Date: 15-Mar-2021 DOI: 10.1126/scitranslmed.abf7872

Using viral load and epidemic dynamics to optimize pooled testing in resource-constrained settings
Brian Cleary et al.
Research Article | Science Translational Medicine Date: 22-Feb-2021 DOI: 10.1126/scitranslmed.abf1568

Lessons from applied large-scale pooling of 133,816 SARS-CoV-2 RT-PCR tests
Netta Barak et al.
Report | Science Translational Medicine Date: 22-Feb-2021 DOI: 10.1126/scitranslmed.abf2823

Development and deployment of COVID-19 vaccines for those most vulnerable
Wayne C. Koff et al.
Review | Science Translational Medicine Date: 3-Feb-2021 DOI: 10.1126/scitranslmed.abd1525

Single-cell RNA sequencing reveals SARS-CoV-2 infection dynamics in lungs of African green monkeys
Emily Speranza et al.
Research Article | Science Translational Medicine Date: 11-Jan-2021 DOI: 10.1126/scitranslmed.abe8146

Stereotypic neutralizing VH antibodies against SARS-CoV-2 spike protein receptor binding domain in COVID-19 patients and healthy individuals
Sang Il Kim et al.
Research Article | Science Translational Medicine Date: 4-Jan-2021 DOI: 10.1126/scitranslmed.abd6990

IgA dominates the early neutralizing antibody response to SARS-CoV-2
Delphine Sterlin et al.
Research Article | Science Translational Medicine Date: 7-Dec-2020 DOI: 10.1126/scitranslmed.abd2223

Enhanced SARS-CoV-2 neutralization by dimeric IgA
Zijun Wang et al.
Research Article | Science Translational Medicine Date: 7-Dec-2020 DOI: 10.1126/scitranslmed.abf1555

Lung transplantation for patients with severe COVID-19
Ankit Bharat et al.
Report | Science Translational Medicine Date: 30-Nov-2020 DOI: 10.1126/scitranslmed.abe4282

Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2
Alexandra Popa et al.
Research Article | Science Translational Medicine Date: 23-Nov-2020 DOI: 10.1126/scitranslmed.abe2555

Prothrombotic autoantibodies in serum from patients hospitalized with COVID-19
Yu Zuo et al.
Research Article | Science Translational Medicine Date: 2-Nov-2020 DOI: 10.1126/scitranslmed.abd3876

Courage in a climate of fear
Abraham Verghese and Eric Topol
Editorial | Science Translational Medicine Date: 19-Oct-2020 DOI: 10.1126/scitranslmed.abf2461

Prospects for a safe COVID-19 vaccine
Barton F. Haynes et al.
Review | Science Translational Medicine Date: 19-Oct-2020 DOI: 10.1126/scitranslmed.abe0948

Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients
Carl A. Pierce et al.
Research Article | Science Translational Medicine Date: 21-Sep-2020 DOI: 10.1126/scitranslmed.abd5487

We’re on our own
H. Holden Thorp
Editorial | Science Translational Medicine Date: 4-Sep-2020 DOI: 10.1126/scitranslmed.abe5793

A comparison of four serological assays for detecting anti-SARS-CoV-2 antibodies in human serum samples from different populations
Ludivine Grzelak et al.
Research Article | Science Translational Medicine Date: 17-Aug-2020 DOI: 10.1126/scitranslmed.abc3103

3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice
Athri D. Rathnayake et al.
Report | Science Translational Medicine Date: 3-Aug-2020 DOI: 10.1126/scitranslmed.abc5332

A colorimetric RT-LAMP assay and LAMP-sequencing for detecting SARS-CoV-2 RNA in clinical samples
Viet Loan Dao Thi et al.
Research Article | Science Translational Medicine  Date: 27-Jul-2020 DOI: 10.1126/scitranslmed.abc7075

An alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates
Jesse H. Erasmus et al.
Research Article | Science Translational Medicine Date: 20-Jul-2020 DOI: 10.1126/scitranslmed.abc9396

Using influenza surveillance networks to estimate state-specific prevalence of SARS-CoV-2 in the United States
Justin D. Silverman et al.
Report | Science Translational Medicine Date: 22-Jun-2020 DOI: 10.1126/scitranslmed.abc1126

Antibody signature mediated by SARS-CoV-2 spike protein immunogens in rabbits
Supriya Ravichandran et al.
Report | Science Translational Medicine Date: 8-Jun-2020 DOI: 10.1126/scitranslmed.abc3539

COVID-19 diagnostics in context
Ralph Weissleder et al.
Perspective | Science Translational Medicine Date: 3-Jun-2020 DOI: 10.1126/scitranslmed.abc1931

A rapidly deployable individualized system for augmenting ventilator capacity
Shriya Srinivasan et al.
Report | Science Translational Medicine Date: 18-May-2020 DOI: 10.1126/scitranslmed.abb9401

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
Timothy P. Sheahan et al.
Research Article | Science Translational Medicine Date: 6-Apr-2020 DOI: 10.1126/scitranslmed.abb5883

New coronavirus outbreak: Framing questions for pandemic prevention
Scott P. Layne, James M. Hyman, David M. Morens, Jeffrey K. Taubenberger
Editorial | Science Translational Medicine Date: 11-Mar-2020 DOI: 10.1126/scitranslmed.abb1469

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News from Science

Science's COVID-19 reporting is supported by the Heising-Simons Foundation and the Pulitzer Center.

Highlighted story: Champagne and questions greet first data showing that a COVID-19 vaccine works

How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes

Visit News from Science for more coronavirus coverage (or use our COVID-19 RSS news feed).

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Letters to the Editor

Investigate the origins of COVID-19
Jesse D. Bloom et al.
Letter to the Editor | Science Date: 14-May-2021 DOI: 10.1126/science.abj0016

Partial immunity and SARS-CoV-2 mutations
William P. Hanage and Colin A. Russell
Letter to the Editor | Science Date: 23-Apr-2021 DOI: 10.1126/science.abi4727

Response—Partial immunity and SARS-CoV-2 mutations
Chadi M. Saad-Roy et al.
Letter to the Editor | Science Date: 23-Apr-2021 DOI: 10.1126/science.abi6719

Appropriate names for COVID-19 variants
Salim S. Abdool Karim et al.
Letter to the Editor | Science Date: 19-Mar-2021 DOI: 10.1126/science.abh0836

Vaccine efficacy probable against COVID-19 variants
Larry L. Luchsinger and Christopher D. Hillyer
Letter to the Editor | Science Date: 12-Mar-2021 DOI: 10.1126/science.abg9461

Social distancing remains key during vaccinations
Marta Galanti et al.
Letter to the Editor | Science Date: 29-Jan-2021 DOI: 10.1126/science.abg2326

Disinfection spreads antimicrobial resistance
Ji Lu and Jianhua Guo
Letter to the Editor | Science Date: 29-Jan-2021 DOI: 10.1126/science.abg4380

Anomalous COVID-19 tests hinder researchers
Lindsey R. Robinson-McCarthy et al.
Letter to the Editor | Science Date: 15-Jan-2021 DOI: 10.1126/science.abf8873

Transparency is key to ethical vaccine research
Preston W. Estep and George M. Church
Letter to the Editor | Science Date: 18-Dec-2020 DOI: 10.1126/science.abf4851

Response—Transparency is key to ethical vaccine research
Christi J. Guerrini et al.
Letter to the Editor | Science Date: 18-Dec-2020 DOI: 10.1126/science.abf4883

Response—Transparency is key to ethical vaccine research
Arthur Caplan and Alison Bateman-House
Letter to the Editor | Science Date: 18-Dec-2020 DOI: 10.1126/science.abf7809

EcoHealth reframing of disease monitoring
Maarten P. M. Vanhove et al.
Letter to the Editor | Science Date: 13-Nov-2020 DOI: 10.1126/science.abe8239

Build international biorepository capacity
Jocelyn P. Colella et al.
Letter to the Editor | Science Date: 13-Nov-2020 DOI: 10.1126/science.abe4813

Response to Vanhove et al. and Colella et al.
Mrinalini Watsa et al.
Letter to the Editor | Science Date: 13-Nov-2020 DOI: 10.1126/science.abe9392

Support U.S. research during COVID-19
Michael M. Crow et al.
Letter to the Editor | Science Date: 30-Oct-2020 DOI: 10.1126/science.abf1225

Airborne transmission of SARS-CoV-2
Kimberly A. Prather et al.
Letter to the Editor | Science Date: 5-Oct-2020 DOI: 10.1126/science.abf0521

University–pharmacy partnerships for COVID-19
Vincent J. Venditto et al.
Letter to the Editor | Science Date: 18-Sep-2020 DOI: 10.1126/science.abe3339

Accumulation of plastic waste during COVID-19
Tanveer M. Adyel
Letter to the Editor | Science Date: 11-Sep-2020 DOI: 10.1126/science.abd9925

Support transgender scientists post–COVID-19
Shaun Turney et al.
Letter to the Editor | Science Date: 4-Sep-2020 DOI: 10.1126/science.abd8933

Controlling the coronavirus narrative
Nita Bharti
Letter to the Editor | Science Date: 14-Aug-2020 DOI: 10.1126/science.abd3662

Conservation needs a COVID-19 bailout
Robert A. McCleery et al.
Letter to the Editor | Science Date: 31-Jul-2020 DOI: 10.1126/science.abd2854

Extinct-in-the-wild species’ last stand
Amanda Trask et al.
Letter to the Editor | Science Date: 31-Jul-2020 DOI: 10.1126/science.abd4560

Nicaragua’s COVID-19 crisis demands a response
Jorge Huete-Pérez and John Hildebrand
Letter to the Editor | Science Date: 24-Jul-2020 DOI: 10.1126/science.abd4975

A community-led approach to COVID-19
Kyle A. Artelle et al.
Letter to the Editor | Science Date: 24-Jul-2020 DOI: DOI: 10.1126/science.abd2107

COVID-19 policies: Remember measles
Debarati Guha-Sapir et al.
Letter to the Editor | Science Date: 17-Jul-2020 DOI: 10.1126/science.abc8637

Restart science stronger after COVID-19
Alan I. Leshner
Letter to the Editor | Science Date: 17-Jul-2020 DOI: 10.1126/science.abd5780

Unnecessary hesitancy on human vaccine tests
Nir Eyal
Letter to the Editor | Science Date: 10-Jul-2020 DOI: 10.1126/science.abc8264

Response—Unnecessary hesitancy on human vaccine tests
Seema K. Shah et al.
Letter to the Editor | Science Date: 10-Jul-2020 DOI: 10.1126/science.abc9380

News from a postpandemic world
Joel Henrique Ellwanger et al.
Letter to the Editor | Science Date: 3-Jul-2020 DOI: 10.1126/science.abd1320

COVID-19's unsustainable waste management
Siming You et al.
Letter to the Editor | Science Date: 26-Jun-2020 DOI: 10.1126/science.abc7778

Pandemics’ historical role in creating inequality
Liliana M. Dávalos et al.
Letter to the Editor | Science Date: 19-Jun-2020 DOI: 10.1126/science.abc8953

Recent immigrants at increased pandemic risk
Pierre Galanaud and Anne Galanaud
Letter to the Editor | Science Date: 19-Jun-2020 DOI: 10.1126/science.abd1098

Aggregating data from COVID-19 trials
Elizabeth L. Ogburn et al.
Letter to the Editor | Science Date: 12-Jun-2020 DOI: 10.1126/science.abc8993

Tenure and promotion after the pandemic
Mala Htun
Letter to the Editor | Science Date: 5-Jun-2020 DOI: 10.1126/science.abc7469

Ease restrictions on U.S. blood donations
Chirag Vasavda et al.
Letter to the Editor | Science Date: 29-May-2020 DOI: 10.1126/science.abc2322

The precarious position of postdocs during COVID-19
M. Arslan Ahmed et al.
Letter to the Editor | Science Date: 29-May-2020 DOI: 10.1126/science.abc5143

COVID-19 recovery can benefit biodiversity
Ryan M. Pearson et al.
Letter to the Editor | Science Date: 22-May-2020 DOI: 10.1126/science.abc1430

COVID-19 spotlights medical diagnostics
Maurycy Jankowski et al.
Letter to the Editor | Science Date: 22-May-2020 DOI: 10.1126/science.abb8952

Impact of COVID-19 on academic mothers
F. Staniscuaski et al.
Letter to the Editor | Science Date: 15-May-2020 DOI: 10.1126/science.abc2740

Support early-career field researchers
D. W. Inouye et al.
Letter to the Editor | Science Date: 15-May-2020 DOI: 10.1126/science.abc1261

Preserve Global South's research capacity
D. Reidpath et al.
Letter to the Editor | Science Date: 15-May-2020 DOI: 10.1126/science.abc2677

Call for transparency of COVID-19 models
C. Michael Barton et al.
Letter to the Editor | Science Date: 1-May-2020 DOI: 10.1126/science.abb8637

Research opportunities in pandemic lockdown
Rajeev Saraswat, Divya Atri Saraswat
Letter to the Editor | Science Date: 30-Apr-2020 DOI: 10.1126/science.abc3372

Protect Indigenous peoples from COVID-19
Lucas Ferrante, Philip M. Fearnside
Letter to the Editor | Science Date: 17-Apr-2020 DOI: 10.1126/science.abc0073

Protecting older adults during social distancing
Ali Jawaid
Letter to the Editor | Science Date: 10-Apr-2020 DOI: 10.1126/science.abb7885

Disinfection threatens aquatic ecosystems
Hong Zhang et al.
Letter to the Editor | Science Date: 10-Apr-2020 DOI: 10.1126/science.abb8905

Permanently ban wildlife consumption
Nian Yang et al.
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb1938

Wildlife consumption ban is insufficient
Hongxin Wang et al.
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb6463

COVID-19 drives new threat to bats in China
Huabin Zhao
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb3088

Travel restrictions violate international law
Benjamin Mason Meier et al.
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb6950

Aggregated mobility data could help fight COVID-19
Caroline O. Buckee et al.
Letter to the Editor | Science Date: 23-Mar-2020 DOI: 10.1126/science.abb8021

Preventing COVID-19 prejudice in academia
Piotr Rzymski, Michał Nowicki
Letter to the Editor | Science Date: 20-Mar-2020 DOI: 10.1126/science.abb4870

Misguided drug advice for COVID-19
Garret A. FitzGerald
Letter to the Editor | Science Date: 20-Mar-2020 DOI: 10.1126/science.abb8034

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Book Reviews

Probing COVID’s complexity in real time
Samuel V. Scarpino
Book Review | Science Date: 20-Nov-2020 DOI: 10.1126/science.abe9731

Better homes and safer spaces
Barbara Brown
Book Review | Science Date: 3-Jul-2020 DOI: 10.1126/science.abc6862

Discounting lives
Audra J. Wolfe
Book Review | Science Date: 12-Jun-2020 DOI: 10.1126/science.abc0164

Tinctures of time and Schrödinger's virus
Luis Campos
Book Review | Science Date: 1-May-2020 DOI: 10.1126/science.abc1732

The other public health crisis
Joanna Schug
Book Review | Science Date: 1-May-2020 DOI: 10.1126/science.abb3582

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Atlas shrugs
H. Holden Thorp
Blog post | Science Date: 18-Aug-2020

Modeling herd immunity
H. Holden Thorp, Valda Vinson, Caroline Ash
Blog post | Science Date: 23-Jun-2020

Guest blogs
H. Holden Thorp
Blog post | Science Date: 12-May-2020

Reading the pandemic data
Jeffrey M. Zacks and Steven L. Franconeri
Blog post | Science Date: 12-May-2020

The end of the handshake?
Cato T. Laurencin and Aneesah McClinton
Blog post | Science Date: 12-May-2020

Drawing the blueprint to a COVID-19 response
H. Holden Thorp
Blog post | Science Date: 27-Apr-2020

Expanding voices during the COVID-19 crisis
H. Holden Thorp
Blog post | Science Date: 7-Apr-2020

Adapting to the crisis
H. Holden Thorp
Blog post | Science Date: 3-Apr-2020

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Additional Content

Coronavirus Investigated video series: A deeper look at the concepts behind coronavirus research

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Video: How diseases rise and fall with the seasons—and what it could mean for coronavirus

Science Facebook Live: How understanding SARS-CoV-2 structure is informing vaccine design and clinical trial